Buy 4-AcO-DMT

$125.00$1,150.00

Name: 4-Aco DMT
Active Ingredient: O-Acetylpsilocin
Use: Managemet of Depression

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Description

Buy 4-AcO-DMT Online

Description
4-AcO-DMT (O-acetylpsilocin), is a novel tryptamine that was discovered in the early 50s. Furthermore It is an O-acetate ester of psilocin. Moreover While there are studies done on the use of serotonin 5-HT2A agonists in treating substance/drug use disorders, the neurological basis of these effects have yet to be elucidated. Nevertheless There is an interesting study done on the effects of 4-Aco-DMT on drug-dependent rats and mice, published in the European Journal of Neuroscience (EJN). Buy 4-AcO-DMT Online

Indication And Uses
1) Treatment Of drug Dependence
2) Management of Depression

About Drug Use
Chronic use of drugs of abuse produce changes and cellular adaptations in neurons located in the VTA (Ventral Tegmental Area) of the brain, which is part of the dopamine mediated reward pathway. Nevertheless These adaptations are mediated by BDNF (brain-derived neurotrophic factor) and are associated with the aversive withdrawal motivation that leads to a drug-dependent state. Furthermore There is growing evidence that suggests that 5-HT2A receptor signaling can regulate the expression of BDNF in the brain. Moreover Both 5-HT and TrkB signaling are involved in modulating long term neuronal survival and plasticity but it is still unknown if these effects occur via a direct 5HT2A interaction or downstream interactions between 5HT2A.

Studies On 4-Aco-DMT
In a study done with 4-Aco-DMT, it was observed that a single administration to the VTA of rats and mice blocks the aversive conditioned response to drug withdrawal as well as the mechanism that switches the drug-naive state to a drug-dependent system. Moreover These studies indicated that 5-HT2A agonists can be used as therapeutic agents to reverse drug dependency and inhibit the aversive withdrawal response. Nevertheless Our batch of 4-AcO-DMT has been used in scientific research as a standard for purity analysis, and has been confirmed as near 100% purity in a published paper. Buy 4-AcO-DMT Online

Side Effects
1) Vivid hallucination
2) Euphoria
3) Altered sense of personalization
4) Rapid heart rate
5) Increase blood pressure

Additional information

Quantity

1 gram, 2 grams, 5 grams, 10 grams, 1 OZ

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